standard compound xav 939 Search Results


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BPS Bioscience standard compound xav 939
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Selleck Chemicals wnt c59
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Tocris small molecular compound xav939
A. Growth curves of A375 and MEL624 cells expressing GFP or WLS-GFP that were treated with 0.5 µM <t>XAV939,</t> a WNT/β-catenin inhibitor, (blue) or DMSO (red and black) in two-dimensional culture, p < 0.001. B,C. Soft agar assay of A375 cells stably expressing GFP or WLS-GFP. Cells were grown in the presence of either 10% control, WNT3A- or WNT5A-conditioned-media. ( B ) Representative photos of soft agar colonies stained with crystal violet after 3 weeks in culture. ( C ) Quantification of the average number of colonies formed, * p < 0.0001. D. Quantification of AXIN2 mRNA in A375 cells expressing either GFP or WLS-GFP. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001. E. Quantification of AXIN2 mRNA in A375 cell lines treated with the WNT/β-catenin inhibitor XAV939 (0.5 µM) or DMSO control for 72 h. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001.
Small Molecular Compound Xav939, supplied by Tocris, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Chembridge compound ressuplied compoud
A. Growth curves of A375 and MEL624 cells expressing GFP or WLS-GFP that were treated with 0.5 µM <t>XAV939,</t> a WNT/β-catenin inhibitor, (blue) or DMSO (red and black) in two-dimensional culture, p < 0.001. B,C. Soft agar assay of A375 cells stably expressing GFP or WLS-GFP. Cells were grown in the presence of either 10% control, WNT3A- or WNT5A-conditioned-media. ( B ) Representative photos of soft agar colonies stained with crystal violet after 3 weeks in culture. ( C ) Quantification of the average number of colonies formed, * p < 0.0001. D. Quantification of AXIN2 mRNA in A375 cells expressing either GFP or WLS-GFP. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001. E. Quantification of AXIN2 mRNA in A375 cell lines treated with the WNT/β-catenin inhibitor XAV939 (0.5 µM) or DMSO control for 72 h. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001.
Compound Ressuplied Compoud, supplied by Chembridge, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Incyte corporation htdo biochemical a172 kynurenine cell compound assay pic50
A. Growth curves of A375 and MEL624 cells expressing GFP or WLS-GFP that were treated with 0.5 µM <t>XAV939,</t> a WNT/β-catenin inhibitor, (blue) or DMSO (red and black) in two-dimensional culture, p < 0.001. B,C. Soft agar assay of A375 cells stably expressing GFP or WLS-GFP. Cells were grown in the presence of either 10% control, WNT3A- or WNT5A-conditioned-media. ( B ) Representative photos of soft agar colonies stained with crystal violet after 3 weeks in culture. ( C ) Quantification of the average number of colonies formed, * p < 0.0001. D. Quantification of AXIN2 mRNA in A375 cells expressing either GFP or WLS-GFP. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001. E. Quantification of AXIN2 mRNA in A375 cell lines treated with the WNT/β-catenin inhibitor XAV939 (0.5 µM) or DMSO control for 72 h. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001.
Htdo Biochemical A172 Kynurenine Cell Compound Assay Pic50, supplied by Incyte corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Lee Laboratories peptidoglycan pg/ps
A. Growth curves of A375 and MEL624 cells expressing GFP or WLS-GFP that were treated with 0.5 µM <t>XAV939,</t> a WNT/β-catenin inhibitor, (blue) or DMSO (red and black) in two-dimensional culture, p < 0.001. B,C. Soft agar assay of A375 cells stably expressing GFP or WLS-GFP. Cells were grown in the presence of either 10% control, WNT3A- or WNT5A-conditioned-media. ( B ) Representative photos of soft agar colonies stained with crystal violet after 3 weeks in culture. ( C ) Quantification of the average number of colonies formed, * p < 0.0001. D. Quantification of AXIN2 mRNA in A375 cells expressing either GFP or WLS-GFP. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001. E. Quantification of AXIN2 mRNA in A375 cell lines treated with the WNT/β-catenin inhibitor XAV939 (0.5 µM) or DMSO control for 72 h. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001.
Peptidoglycan Pg/Ps, supplied by Lee Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Shimadzu Corporation compound
A. Growth curves of A375 and MEL624 cells expressing GFP or WLS-GFP that were treated with 0.5 µM <t>XAV939,</t> a WNT/β-catenin inhibitor, (blue) or DMSO (red and black) in two-dimensional culture, p < 0.001. B,C. Soft agar assay of A375 cells stably expressing GFP or WLS-GFP. Cells were grown in the presence of either 10% control, WNT3A- or WNT5A-conditioned-media. ( B ) Representative photos of soft agar colonies stained with crystal violet after 3 weeks in culture. ( C ) Quantification of the average number of colonies formed, * p < 0.0001. D. Quantification of AXIN2 mRNA in A375 cells expressing either GFP or WLS-GFP. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001. E. Quantification of AXIN2 mRNA in A375 cell lines treated with the WNT/β-catenin inhibitor XAV939 (0.5 µM) or DMSO control for 72 h. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001.
Compound, supplied by Shimadzu Corporation, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BASF polyethylenimine; mw 1300 basf- 6 lupasol g20-aptac adduct
A. Growth curves of A375 and MEL624 cells expressing GFP or WLS-GFP that were treated with 0.5 µM <t>XAV939,</t> a WNT/β-catenin inhibitor, (blue) or DMSO (red and black) in two-dimensional culture, p < 0.001. B,C. Soft agar assay of A375 cells stably expressing GFP or WLS-GFP. Cells were grown in the presence of either 10% control, WNT3A- or WNT5A-conditioned-media. ( B ) Representative photos of soft agar colonies stained with crystal violet after 3 weeks in culture. ( C ) Quantification of the average number of colonies formed, * p < 0.0001. D. Quantification of AXIN2 mRNA in A375 cells expressing either GFP or WLS-GFP. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001. E. Quantification of AXIN2 mRNA in A375 cell lines treated with the WNT/β-catenin inhibitor XAV939 (0.5 µM) or DMSO control for 72 h. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001.
Polyethylenimine; Mw 1300 Basf 6 Lupasol G20 Aptac Adduct, supplied by BASF, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ICI Pharmaceuticals phf-binding compounds
A. Growth curves of A375 and MEL624 cells expressing GFP or WLS-GFP that were treated with 0.5 µM <t>XAV939,</t> a WNT/β-catenin inhibitor, (blue) or DMSO (red and black) in two-dimensional culture, p < 0.001. B,C. Soft agar assay of A375 cells stably expressing GFP or WLS-GFP. Cells were grown in the presence of either 10% control, WNT3A- or WNT5A-conditioned-media. ( B ) Representative photos of soft agar colonies stained with crystal violet after 3 weeks in culture. ( C ) Quantification of the average number of colonies formed, * p < 0.0001. D. Quantification of AXIN2 mRNA in A375 cells expressing either GFP or WLS-GFP. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001. E. Quantification of AXIN2 mRNA in A375 cell lines treated with the WNT/β-catenin inhibitor XAV939 (0.5 µM) or DMSO control for 72 h. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001.
Phf Binding Compounds, supplied by ICI Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ASINEX Inc compounds gjp49
A. Growth curves of A375 and MEL624 cells expressing GFP or WLS-GFP that were treated with 0.5 µM <t>XAV939,</t> a WNT/β-catenin inhibitor, (blue) or DMSO (red and black) in two-dimensional culture, p < 0.001. B,C. Soft agar assay of A375 cells stably expressing GFP or WLS-GFP. Cells were grown in the presence of either 10% control, WNT3A- or WNT5A-conditioned-media. ( B ) Representative photos of soft agar colonies stained with crystal violet after 3 weeks in culture. ( C ) Quantification of the average number of colonies formed, * p < 0.0001. D. Quantification of AXIN2 mRNA in A375 cells expressing either GFP or WLS-GFP. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001. E. Quantification of AXIN2 mRNA in A375 cell lines treated with the WNT/β-catenin inhibitor XAV939 (0.5 µM) or DMSO control for 72 h. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001.
Compounds Gjp49, supplied by ASINEX Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Medicilon Inc compound syntheses
A. Growth curves of A375 and MEL624 cells expressing GFP or WLS-GFP that were treated with 0.5 µM <t>XAV939,</t> a WNT/β-catenin inhibitor, (blue) or DMSO (red and black) in two-dimensional culture, p < 0.001. B,C. Soft agar assay of A375 cells stably expressing GFP or WLS-GFP. Cells were grown in the presence of either 10% control, WNT3A- or WNT5A-conditioned-media. ( B ) Representative photos of soft agar colonies stained with crystal violet after 3 weeks in culture. ( C ) Quantification of the average number of colonies formed, * p < 0.0001. D. Quantification of AXIN2 mRNA in A375 cells expressing either GFP or WLS-GFP. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001. E. Quantification of AXIN2 mRNA in A375 cell lines treated with the WNT/β-catenin inhibitor XAV939 (0.5 µM) or DMSO control for 72 h. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001.
Compound Syntheses, supplied by Medicilon Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BUCHI AG spray dried dispersion of compound i
A. Growth curves of A375 and MEL624 cells expressing GFP or WLS-GFP that were treated with 0.5 µM <t>XAV939,</t> a WNT/β-catenin inhibitor, (blue) or DMSO (red and black) in two-dimensional culture, p < 0.001. B,C. Soft agar assay of A375 cells stably expressing GFP or WLS-GFP. Cells were grown in the presence of either 10% control, WNT3A- or WNT5A-conditioned-media. ( B ) Representative photos of soft agar colonies stained with crystal violet after 3 weeks in culture. ( C ) Quantification of the average number of colonies formed, * p < 0.0001. D. Quantification of AXIN2 mRNA in A375 cells expressing either GFP or WLS-GFP. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001. E. Quantification of AXIN2 mRNA in A375 cell lines treated with the WNT/β-catenin inhibitor XAV939 (0.5 µM) or DMSO control for 72 h. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001.
Spray Dried Dispersion Of Compound I, supplied by BUCHI AG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


A. Growth curves of A375 and MEL624 cells expressing GFP or WLS-GFP that were treated with 0.5 µM XAV939, a WNT/β-catenin inhibitor, (blue) or DMSO (red and black) in two-dimensional culture, p < 0.001. B,C. Soft agar assay of A375 cells stably expressing GFP or WLS-GFP. Cells were grown in the presence of either 10% control, WNT3A- or WNT5A-conditioned-media. ( B ) Representative photos of soft agar colonies stained with crystal violet after 3 weeks in culture. ( C ) Quantification of the average number of colonies formed, * p < 0.0001. D. Quantification of AXIN2 mRNA in A375 cells expressing either GFP or WLS-GFP. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001. E. Quantification of AXIN2 mRNA in A375 cell lines treated with the WNT/β-catenin inhibitor XAV939 (0.5 µM) or DMSO control for 72 h. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001.

Journal: EMBO Molecular Medicine

Article Title: WLS inhibits melanoma cell proliferation through the β-catenin signalling pathway and induces spontaneous metastasis

doi: 10.1002/emmm.201201486

Figure Lengend Snippet: A. Growth curves of A375 and MEL624 cells expressing GFP or WLS-GFP that were treated with 0.5 µM XAV939, a WNT/β-catenin inhibitor, (blue) or DMSO (red and black) in two-dimensional culture, p < 0.001. B,C. Soft agar assay of A375 cells stably expressing GFP or WLS-GFP. Cells were grown in the presence of either 10% control, WNT3A- or WNT5A-conditioned-media. ( B ) Representative photos of soft agar colonies stained with crystal violet after 3 weeks in culture. ( C ) Quantification of the average number of colonies formed, * p < 0.0001. D. Quantification of AXIN2 mRNA in A375 cells expressing either GFP or WLS-GFP. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001. E. Quantification of AXIN2 mRNA in A375 cell lines treated with the WNT/β-catenin inhibitor XAV939 (0.5 µM) or DMSO control for 72 h. AXIN2 expression was normalized to GAPDH , two-way ANOVA, p < 0.0001.

Article Snippet: Small molecular compound XAV939 (Tocris Bioscience, Ellisville, MO, USA), CHIR99021 (Cayman Chemical) or 0.1% DMSO were included in the culture media.

Techniques: Expressing, Soft Agar Assay, Stable Transfection, Control, Staining